This study investigates the influence of uptake of courses and finance availability on the expansion strategies in public training institutions with reference to the Kenya Medical Training College. The specific objectives of the study are to: reveal the influence of uptake of courses on the success of expansion strategies in the public training institutions and; assess the influence of finances on the success of expansion strategies in the public training institutions. This study is based on the Ansoff Growth Matrix (AGM) and the theory of customer responsiveness. It adopts the descriptive survey design. The study focuses on 2393 KMTC officers from the 73 KMTC campuses in Kenya, 42 ministries of health officials in the 42 counties that have KMTC campuses and 42 local leaders from those counties that have KMTC campuses. The total targeted study participants were thus 2477. From these, 10% (248 persons) were sampled. The study used purposive and stratified random sampling techniques to obtain the study sample. Primary data was collected using structured questionnaires and interviews. Data from questionnaires were analysed using the Statistical Package for the Social Sciences (SPSS) version 24. Descriptive statistics (frequencies, percentages, and means) were used to describe the central tendencies of the data. In addition, inferential statistics (Pearson Correlation and Multiple Regression Analysis) were also used. Data from key informants were analysed using content analysis techniques. The findings show that the two study variables influenced the success of expansion strategies at KMTC campuses. In this regard, Pearson correlation shows that there was statistical significant relationship between uptake of courses (r=.308, p<0.001) and; finance availability (r=0.673, p<0.001) and success of expansion strategies. These findings show that finance availability was the strongest factor that influenced the success of expansion strategies. As such, the success of expansion strategies can only be successful if the college put in place strategies aimed at ensuring that there were sufficient finances. This could go on to enhance the development of facilities and equipping them. An effort aimed at ensuring that new campuses had a high intake of students could also contribute to the level of success of expansion strategies at KMTC. High intakes could enhance the revenue generation, further enhancing the funding and success of new KMTC campuses.